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N- Synthesis method of pyridine derivative through N-annulation reaction
N- Synthesis method of pyridine derivative through N-annulation reaction
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机译:N-N环化反应合成吡啶衍生物的方法
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摘要
The present invention provides a novel method for the easy, simple and efficient synthesis of various types of pyridine derivatives through an N-cyclization reaction under an organic catalyst. This synthesis method can be carried out without introducing the functional ps of oximes, imines or azides which have been conventionally used for the production of pyridine, but it is possible to use , -unsaturated aldehyde compound, ammonium acetate And a ketone compound to easily and simply provide various types of pyridine derivatives. The pyridine derivatives prepared by this synthesis method are very useful technologies widely applicable to the synthesis of pharmaceutical intermediates, natural products, agricultural chemicals, dyes, and electronic materials.
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