ACTIVATED MACROPHAGE TARGETABLE DRUG DELIVERY SYSTEMS FOR TREATMENT OF ATHEROSCLEROSIS AND METHODS OF PREPARATION

摘要

The present invention relates to a drug delivery system for the treatment of atherosclerosis, comprising a biocompatible amphiphilic polymer and a hydrophobic drug, wherein the drug delivery system of the present invention selectively targets the activated macrophages in the atherosclerotic plaque, It is possible to prevent the spread of the disease at all stages of the occurrence, progression and rupture of atherosclerosis, or to prevent various complications due to arteriosclerosis.