Method for preventing of oocyte aging and enhancing developmental rate utilizing melatonin

摘要

The present invention relates to a method for preventing aging of an oocyte and improving an embryo development rate using the melatonin, and more particularly, to a method for improving an aging oocyte by treating melatonin to reduce reactive oxygen species (ROS) And to a method for preventing aging of the oocyte by increasing the expression of actin filaments of senescent oocyte and improving the embryo development rate. The present invention relates to a method for improving the quality of oocytes by preventing melatonin from aging of oocytes matured over time and improving the quality of the in vitro culture embryo and prolonging the culture period in vitro, Thereby improving the development rate.