POLYMORPHIC FORMS OF AFATINIB FREE BASE AND AFATINIB DIMALEATE

摘要

The present invention relates to crystalline forms of apatinate and dimaleate salts thereof. The present invention also relates to a process for preparing crystalline forms of apatinate and dimaleate salts thereof. The present invention also relates to a pharmaceutical composition of crystalline form of apatipine dimaleate and their use in the treatment of patients in need thereof.