首页> 外国专利> PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING DIABETES MELLITUS CONTAINING AMODIAQUINE AND ANTIDIABETIC DRUG

PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING DIABETES MELLITUS CONTAINING AMODIAQUINE AND ANTIDIABETIC DRUG

机译:用于预防或治疗含有阿马喹和抗糖尿病药物的糖尿病的药物组合物

摘要

The present invention relates to a pharmaceutical composition for preventing or treating diabetes, and controlling a side effect from peroxisome proliferator-activated receptor-gamma (PPAR- γ) activation, wherein the pharmaceutical composition comprises (a) an amodiaquine compound or a pharmaceutically acceptable salt thereof and (b) an antidiabetic drug as active ingredients. Specifically, the composition prevents or treats simultaneously one or more selected from the group consisting of type 2 diabetes reactive to PPAR-γ activation, and obesity, dyslipidemia, cardiovascular diseases, and fatty cirrhosis reactive to peroxisome proliferator-activated receptor-alpha (PPAR-α) activation.
机译:本发明涉及一种用于预防或治疗糖尿病并控制过氧化物酶体增殖物激活的受体-γ(PPAR-γ)激活的副作用的药物组合物,其中所述药物组合物包含(a)氨二喹化合物或药学上可接受的盐。 (b)抗糖尿病药作为有效成分。具体而言,该组合物同时预防或治疗选自对PPAR-γ活化有反应性的2型糖尿病,对过氧化物酶体增殖物活化的受体α(PPAR-有反应性)的肥胖,血脂异常,心血管疾病和脂肪性肝硬化。 α)激活。

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