TARGETED SYNTHETIC NANOCARRIERS WITH PH SENSITIVE RELEASE OF IMMUNOMODULATORY AGENTS

摘要

The present invention relates to a composition and related method of a synthetic nano-carrier comprising an immunoregulatory agent that targets the site of action of a cell such as an antigen presenting cell (APC) and is separated from the synthetic nano-carrier in a pH-sensitive manner. And also relates to compositions and methods relating to synthetic nano-carriers that encapsulate an instability immunomodulator that is separated from the synthetic nano-carriers in a pH-sensitive manner.