首页> 外国专利> STK32C Producing method of senescence-accelerated animal model by causing deficiency of STK32C gene and uses thereof

STK32C Producing method of senescence-accelerated animal model by causing deficiency of STK32C gene and uses thereof

机译:STK32C基因缺失引起的衰老加速动物模型的制备方法及其用途

摘要

The present invention relates to a method for producing an aging-accelerated animal model in which the STK32C (Serine / threonine kinase 32C) gene has been deleted and its use. The present invention includes a step of introducing a target vector into which a STK32C (Serine / threonine kinase 32C) gene has been deleted and transforming it. In the heterozygous mouse (STK32C (+/-)) produced by the above method, It is expected that it can be usefully used in aging researches such as development of anti - aging substances by confirming the weight, subcutaneous fat, dermal layer, back bending and wound healing delay.
机译:本发明涉及其中STK32C(丝氨酸/苏氨酸激酶32C)基因已被删除的,加速衰老的动物模型的制备方法及其用途。本发明包括导入已缺失STK32C(丝氨酸/苏氨酸激酶32C)基因的靶载体并对其进行转化的步骤。在通过上述方法生产的杂合小鼠(STK32C(+/-))中,通过确认体重,皮下脂肪,真皮层,背部等,有望将其用于抗衰老物质开发等衰老研究。弯曲和伤口愈合延迟。

著录项

  • 公开/公告号KR101818365B1

    专利类型

  • 公开/公告日2018-01-12

    原文格式PDF

  • 申请/专利权人 동국대학교 산학협력단;

    申请/专利号KR20160099458

  • 发明设计人 이창훈;이호;

    申请日2016-08-04

  • 分类号C12N15/85;A01K67/027;G01N33/50;

  • 国家 KR

  • 入库时间 2022-08-21 12:38:38

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