1-- Novel sulfonyloxymethylphosphonate derivatives and process for preparing diisopropyl 1-trityloxymethyl-cyclopropyloxymethylphosphonate using the same

摘要

The present invention relates to a diisopropyl ((1- (trityloxymethyl) -cyclopropyl) oxy) methylphosphonate compound of the following formula 2, which is an important intermediate in the synthesis of a nucleotide analogue of the formula 1 under development as an antiviral agent / RTI The present invention also relates to novel sulfonyloxymethylphosphonate compounds of formula (3) which are usefully employed as intermediates in the preparation of compounds of formula (2). [Chemical Formula 1] (2) (3) Wherein R 'and R are as defined in the specification.