The pharmaceutical compositions for prevention or treatment of inflammatory spine disease containing Scolopendra subspinipes and Peony as an active ingredient

摘要

The present invention relates to a pharmaceutical composition for the prevention and treatment of inflammatory spinal diseases, comprising a peony and a pit extract as an active ingredient, wherein the peony and pit mixed extracts exhibit a concentration-dependent inhibitory effect on nitric oxide production and cytokine production, And it was confirmed that ear edema was alleviated in a concentration dependent manner by the mixed extract in ear edema-induced mouse model. Further, it was confirmed that ear edema was alleviated by the mixed extract in ear edema-induced mouse model, It was confirmed that the mixed extract of the present invention had the best inhibitory effect on inflammation. As a result, it was confirmed that the pain was alleviated and the disk was improved by administering it as a herb to a patient with herniated disc herniation. The composition is useful for the prevention and treatment of inflammatory spinal diseases It can be used and may be useful to use acupuncture for the prevention and treatment of inflammatory spinal disease.