SHP-1/-2 A pharmaceutical composition for preventing or treating neurodegenerative diseases comprising inhibitor for expressing or activating of SHP-1/-2

摘要

The present invention relates to a pharmaceutical composition for preventing or treating degenerative brain diseases comprising an agent capable of inhibiting the expression or activity of SHP-1 / -2, a method for preventing or treating degenerative brain diseases by administering the above pharmaceutical composition, A composition for diagnosing a degenerative brain disease, a kit for diagnosing a degenerative brain disease comprising the diagnostic composition, and a method for providing information for diagnosing a degenerative brain disease using the kit or the kit. Since the agent capable of inhibiting the expression or activity of SHP-1 / -2 of the present invention can inhibit signal transduction caused by the transfer of? -Sinuclene to the adjacent cells, the cell of? -Sinuclene Can be usefully used as a therapeutic agent for degenerative brain diseases by reducing toxic effects. Further, the agent capable of inhibiting the expression or activity of SHP-1 / -2 of the present invention can be an important clue to elucidate the pathogenesis of degenerative brain diseases. Therefore, It can be used to overcome the disease.