COMPOSITION FOR SCREENING STAGE OF ALZHEIMERamp;prime;S DISEASE PROGRESSION BY USING BETA AMYLOID OLIGOMER OF NASAL FLUID SAMPLE AND METHOD FOR SCREENING STAGE OF ALZHEIMERamp;prime;S DISEASE PROGRESSION BY USING SAME

摘要

The present invention relates to a composition for screening a stage of Alzheimer′s disease progression by using nasal fluid and a method for screening a stage of Alzheimer′s disease progression by using the same. More specifically, the present invention relates to a composition for screening a stage of Alzheimer′s disease progression which comprises a formulation for measuring levels of the expression of a beta amyloid oligomer of 56 kDa and a beta amyloid oligomer of 72 kDa in a nasal sample, a kit for screening a stage of Alzheimer′s disease progression, and a method for screening the state of Alzheimer′s disease progression which comprises a step of measuring levels of the expression of beta amyloid oligomers of 56 kDa and 72 kDa in a nasal sample. In addition, the present invention relates to a method for screening a therapeutic agent for mild or severe Alzheimer′s disease, the method comprising a step of measuring levels of expression of beta amyloid oligomers of 56 kDa and 72 kDa in a nasal sample, and a kit for screening a therapeutic agent for mild or severe Alzheimer′s disease, the kit comprising a formulation for measuring levels of expression of beta amyloid oligomers of 56 kDa and 72 kDa in a nasal sample.;COPYRIGHT KIPO 2018