Composition for Preventing or Treating of Degenerative Brain Disease Comprising Prolyl Oligopeptidase Inhibitor as Active Ingredient

摘要

The present invention relates to a composition for preventing or treating degenerative brain disease comprising a prolyl oligopeptidase inhibitor as an active ingredient. According to the present invention, the composition inhibits activation of prolyl oligopeptidase, and provides an effect of treating or preventing disease by inhibiting a protein revelation level of α-synuclein. Therefore, the composition can be helpfully used for preventing or treating degenerative brain disease such as synucleinopathy.