The present invention relates to a food composition for suppressing an anticancer drug resistance or a stress hormone related disease which contains rare ginsenoside CSH1 (Rg6) as an active ingredient. CSH1 (Rg6) promotes binding of BRCA1 and Rad51, Induced γ-tubulin expression and inhibited the resistance to taxol in cancer cells. Therefore, the CSH1 (Rg6) is expected to be useful for foods that inhibit the anticancer drug resistance in chemotherapy, and is expected to be applicable to foods for the improvement of stress hormone-related diseases.
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