METHODS FOR PRODUCING GUANIDINE, METACRYLOYLGUANIDINE, METACRYLOYUANIDINE SALT, POLYMER AND COPOLYMER OF METACRYLOYLGUANIDINE SALT AND THE PRODUCED POLYMER AND COPOLYMER

摘要

FIELD: chemistry.SUBSTANCE: invention relates to the chemistry of guanidine-containing low-molecular and high-molecular compounds and can find use in the preparation of drugs that can suppress the growth of bacteria. Specifically, the invention relates to a process for the preparation of a salt of methacryloylguanidine, which involves the preparation of methacryloylguanidine by the reaction of guanidine and methyl methacrylate in an organic solvent and the reaction of methacryloylguanidine with an acid. Process is characterized in that as an organic solvent, acetonitrile is used, and as an acid, acetic, trifluoroacetic or methacrylic acid. Invention also relates to processes for the preparation of a polymer and a copolymer of a methacryloylguanidine salt, a polymer and a methacryloylguanidine salt copolymer prepared by said methods.EFFECT: invention can find application in the preparation of drugs that can suppress the growth of bacteria.8 cl, 13 dwg, 29 ex, 1 tbl