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METHOD FOR FORECASTING AND / OR PREVENTION OF OVER WEIGHT, OBESITY AND / OR THEIR COMPLICATIONS BY ANALYSIS OF EXPRESSION OF GENES

机译:通过基因表达分析预测和/或预防超重,肥胖和/或其并发症的方法

摘要

The invention relates to a method for predicting and/or preventing overweight, obesity and/or disorders associated with overweight or obesity, said method comprising the detection of the product of the expression of the LRP11 gene, and also of LRP11 in combination with certain genes. In addition, the method permits a personalised treatment to be designed for a subject with the risk of developing said diseases, and permits the effectiveness of a treatment, involving the ingestion of leptin, to be evaluated. The invention also relates to: the use of the products of expression of the genes according to the invention as biomarkers for said diseases; a kit that detects the products of expression; and the use of same for said indications.
机译:本发明涉及一种预测和/或预防超重,肥胖和/或与超重或肥胖有关的疾病的方法,所述方法包括检测LRP11基因表达产物以及与某些基因结合的LRP11表达。另外,该方法允许针对患有发生所述疾病的风险的受试者设计个性化治疗,并允许评估包括摄入瘦素的治疗的有效性。本发明还涉及:根据本发明的基因表达产物作为所述疾病的生物标志物的用途;检测表达产物的试剂盒;以及上述指示的用法。
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