COMBINATION OF KINURENIN AND ANTIGEN REPRESENTING CELLS (APC) AS A THERAPEUTIC MEDICINES AND METHOD FOR THEIR APPLICATION IN IMMUNOMODULATION

摘要

This invention provides combinations of kynurenine and antigen presenting cells (APC) for modulating immune tolerance, wherein the combinations may be used to modulate an autoimmune response, which may be of use in the treatment of Type 1 Diabetes (T1D) or alopecia areata (AA). Uses of kynurenine and antigen presenting cells (APC) as an immune modulator for the treatment of T1D or AA are also provided.