MICROFLUID CELL FOR THE CONDITIONS OF CRYSTALLIZATION OF PROTEINS FROM THE CHARACTERISTICS OF SMALL-ANGLE SCATTERING OF X-RAY RAYS

摘要

The utility model relates to devices for determining the crystallization conditions of protein macromolecules and can be used to obtain protein crystals in order to determine the structure of protein molecules of industrial and medical importance. The technical result is the ability to quickly determine the optimal conditions for the crystallization of proteins. To achieve this, a microfluidic cell has been proposed for determining the crystallization conditions of proteins according to the characteristics of small-angle X-ray scattering, comprising a housing with a centrally located opening in which a crystallization chamber is formed, connected by microchannels with openings for the input and output of protein solutions, on the outer sides of which there are windows of material transparent to x-ray and optical radiation. The windows are made of mica or quartz glass. The body consists of three thermally welded plates made of polymethyl methacrylate. 2 Cpf., 7 ill., 1 tab.