METHOD FOR TREATMENT OF ACUTE BURN TOXEMIA OF ORGANISM AND METHOD FOR PRODUCTION OF PREPARATION FOR TREATMENT OF ACUTE BURNTOXEMIA OF ORGANISM

摘要

FIELD: medicine.;SUBSTANCE: method for treatment involving administration of a biologically active drug into the body is described, wherein a hyperimmune anti-burn antitoxic serum of mammals is administered as a specific preparation, three times - 24, 48 and 112 hours after the burn injury, subcutaneously at a dose of 100-125 mg/kg of weight to young and 150-190 mg/kg to adult animals. The group of inventions also relates to a method for production of a preparation for treatment of acute burn toxemia of the organism characterized by preliminar obtaining of a burn antigen, then the resulting burn antigen with incomplete Freud's adjuvant in a ratio of 1:1 is used for the hyperimmunization of rabbits, sheep, pigs, cows or horses, serum is isolated in 18 hours, the antibody titer and protein content are determined and adjusted to a concentration of 25-30 mg/ml, then the serum is subjected to radiation sterilization by gamma irradiation.;EFFECT: increased detoxification effect, prevented development of burn toxemia, without systematic, multiple transfusion of blood, plasma, blood substitutes, albumin, protein.;2 cl, 7 ex, 1 tbl