首页> 外国专利> APPLICATION OF ALBIZZIA CHINENSIS EXTRACT IN PREPARATION OF MEDICINE FOR TREATMENT OF GASTRIC ULCER

APPLICATION OF ALBIZZIA CHINENSIS EXTRACT IN PREPARATION OF MEDICINE FOR TREATMENT OF GASTRIC ULCER

机译:中华芦荟提取物在胃溃疡治疗药物制备中的应用。

摘要

FIELD: medicine; pharmaceuticals; chemistry.;SUBSTANCE: invention relates to pharmaceutical industry and is a method of preparation of an Albizzia chinensis (Osbeck) Merr extract, comprising extraction of the tree bark of Albizzia chinensis (Osbeck) Merr 80-95% EtOH in H2O to obtain an extract, volume/weight ratio of EtOH to the Albizzia chinensis tree bark is from 3:1 to 5:1; and purifying the resulting extract by column chromatography with a polyamide adsorbent when eluting successively with 10-30% and 40-80% solution of EtOH in H2O, during purification, said extract is dissolved in 10-30% EtOH/H2O.;EFFECT: invention provides inhibition of H+/ K+-ATPase activity in the stomach.;7 cl, 2 dwg, 3 tbl, 3 ex
机译:领域:医学;药品;化学领域;本发明涉及制药工业,并且是制备白花蛇舌草(Osbeck)Merr提取物的方法,包括提取H 2上的白花蛇舌草(Osbeck)Merr 80-95%EtOH。 O以获得提取物,EtOH与白毛树树皮的体积/重量比为3:1至5:1;当用10-30%和40-80%的EtOH在H 2 O中的溶液连续洗脱时,用聚酰胺吸附剂通过柱色谱法纯化所得提取物,在纯化过程中,将所述提取物溶于10- 30%EtOH / H 2 O .;效果:本发明抑制了胃中H + / K + -ATPase的活性。7 cl,2 dwg,3 tbl,3 ex

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