.;EFFECT: compounds show a pronounced antiviral activity along with low toxicity – the chemotherapeutic index of the compounds (1a-e) is much higher than that of the reference drugs.;1 cl, 1 tbl, 5 ex"/> APPLICATION OF ALIPHATIC IMINO-DERIVATIVES OF CAMPFOR AS EFFECTIVE INHIBITORS OF REPRODUCTION OF INFLUENZA VIRUS STRAIN A/CALIFORNIA/07/09 (H1N1) PDM09 AND A/PUERTO RICO/8/34 (H1N1)
首页> 外国专利> APPLICATION OF ALIPHATIC IMINO-DERIVATIVES OF CAMPFOR AS EFFECTIVE INHIBITORS OF REPRODUCTION OF INFLUENZA VIRUS STRAIN A/CALIFORNIA/07/09 (H1N1) PDM09 AND A/PUERTO RICO/8/34 (H1N1)

APPLICATION OF ALIPHATIC IMINO-DERIVATIVES OF CAMPFOR AS EFFECTIVE INHIBITORS OF REPRODUCTION OF INFLUENZA VIRUS STRAIN A/CALIFORNIA/07/09 (H1N1) PDM09 AND A/PUERTO RICO/8/34 (H1N1)

机译:CAMPFOR的脂肪亚胺衍生物作为流感病毒A / CaliforniaA / 07/09(H1N1)PDM09和A / PUERTO RICO / 8/34(H1N1)繁殖的有效抑制剂

摘要

FIELD: medicine.;SUBSTANCE: invention relates to the field of medicine and pharmaceutics. Use of imino-derivatives of camphor of general formula (I), where n=1, 2, 3, 4, 5, as inhibitors of reproduction of the influenza virus strain A/California/07/09 (H1N1) pdm09 and A/Puerto Rico/8/34 (H1N1). .;EFFECT: compounds show a pronounced antiviral activity along with low toxicity – the chemotherapeutic index of the compounds (1a-e) is much higher than that of the reference drugs.;1 cl, 1 tbl, 5 ex
机译:技术领域本发明涉及医学和药学领域。通式(I)的樟脑亚氨基衍生物(其中n = 1、2、3、4、5)作为流感病毒A / California / 07/09(H1N1)pdm09和A /波多黎各/ 8/34(H1N1)。 。;效果:化合物显示出显着的抗病毒活性以及低毒性–的化学治疗指数化合物(1a-e)远远高于参考药物。; 1 cl,1 tbl,5 ex

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