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METHOD FOR MEASURING THE CONCENTRATION OF CIRCULATING MODIFIED LOW-DENSITY LIPOPROTEINS IN HUMAN BLOOD SERUM

机译:测定人血中循环修饰的低密度脂蛋白浓度的方法

摘要

FIELD: medicine.;SUBSTANCE: invention relates to medicine and clinical biochemistry and can be used in laboratory diagnostics for determining circulating modified low-density lipoproteins (cmLDL) for diagnostic and therapeutic purposes. Method for quantitatively determining the content of circulating modified low-density lipoproteins in blood of patients comprises measuring the level of desialylate apoprotein B-100 by enzyme multipled immunoassay with the use of ricin agglutinin PKA 120, which binds to terminal galactose in desialylate apoprotein B-100.;EFFECT: proposed is a method for quantitatively determining the content of circulating modified low-density lipoproteins in blood.;1 cl, 2 ex
机译:技术领域本发明涉及医学和临床生物化学,并且可以用于实验室诊断中以测定循环修饰的低密度脂蛋白(cmLDL)以用于诊断和治疗目的。定量测定患者血液中循环修饰的低密度脂蛋白含量的方法包括:通过使用蓖麻蛋白凝集素PKA 120进行酶多重免疫测定,测量脱唾液酸脱辅基载脂蛋白B-100的水平,该蛋白与脱唾液酸载脂蛋白B-端的半乳糖结合100 .;效果:提出了一种定量测定血液中循环修饰的低密度脂蛋白含量的方法。; 1 cl,2 ex

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