首页> 外国专利> MEANS INCLUDING PERFLUORIDECARBON EMULSION (VARIANTS), ITS USE AND METHOD OF CREATING REVERSIBLE PHARMACOLOGICALLY INDUCED HYPOMETABOLISM AND HYPOTHERMIA

MEANS INCLUDING PERFLUORIDECARBON EMULSION (VARIANTS), ITS USE AND METHOD OF CREATING REVERSIBLE PHARMACOLOGICALLY INDUCED HYPOMETABOLISM AND HYPOTHERMIA

机译:包括全氟化碳乳液(变体)的方法,其用途和创建可逆的药理学上引起的低代谢和低体温的方法

摘要

FIELD: pharmaceuticals.;SUBSTANCE: claimed group of inventions relates to pharmaceutical composition intended to provide an agent for induced hypometabolism and hypothermia in mammals. Pharmaceutical composition includes a beta-blocker propranolol, sympatholitic reserpine, an antianginal drug ivabradine, an antihistamine drug diphenhydramine, serotonin hydrochloride, neuroleptic agent with hypothermic effect of pericyazine, antithyroid agent propicil, magnesium sulfate and pharmaceutically acceptable solvent, in the amounts indicated in the claims. Agent further comprises a carrier, which is a perfluorocarbon emulsion. Ratio of the volume of said pharmaceutical composition and the volume of said carrier is from 1:2 to 1:3. Medicament may further comprise a perfluorocarbon emulsion saturated with an inert gas, preferably xenon.;EFFECT: invention provides use of a new agent in emergency medicine.;9 cl, 2 dwg, 2 ex
机译:药物组合物,其旨在提供用于在哺乳动物中诱导低代谢和低体温的药剂。药物组合物包括β-受体阻滞剂普萘洛尔,交感性利血平,抗心绞痛药物伊伐布雷定,抗组胺药苯海拉明,盐酸5-羟色胺,具有哌拉嗪降温作用的抗精神病药,抗甲状腺药丙脯醇,硫酸镁和药学上可接受的溶剂,其用量在索赔。试剂还包含载体,其为全氟化碳乳液。所述药物组合物的体积与所述载体的体积之比为1:2至1:3。药物可进一步包含用惰性气体(优选氙气)饱和的全氟化碳乳液。效果:本发明提供了新药物在急诊医学中的用途。9cl,2 dwg,2 ex

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