首页> 外国专利> DIAGNOSTIC METHOD FOR DETERMINING THE PRESENCE AND AMOUNT OF HUMAN INTERLEUKIN-3 IN A SAMPLE USING NOVEL IL-3 ANTIBODIES

DIAGNOSTIC METHOD FOR DETERMINING THE PRESENCE AND AMOUNT OF HUMAN INTERLEUKIN-3 IN A SAMPLE USING NOVEL IL-3 ANTIBODIES

机译:用新颖的IL-3抗体测定样品中人白细胞介素3的含量和含量的诊断方法

摘要

For determining the presence and amount of human IL-3 in a sample, the present invention provides a diagnostic method, wherein an anti-IL-3-antibody, fr agment or construct thereof is added to said sample under conditions which allow for binding said antibody, fragment or construct thereof to IL-3 and detecting the amount of antibody bound IL-3 in said sample, wherein the anti-IL-3-antibody is clone 13. Further subject matter of the present invention are the novel antibody clone 13, a nucleic acid encoding said antibody and a hybridoma cell line which produces antibody clone 13. A diagnostic assay kit contains all necessary reagents and materials for performing such assay, preferably an ELISA assay and especially preferably contains antibody clones 13 and 11.
机译:为了确定样品中人IL-3的存在和含量,本发明提供了一种诊断方法,其中在允许结合所述IL-3抗体的条件下,将抗IL-3-抗体,片段或其构建体加入所述样品中。抗IL-3抗体,其片段或构建体并检测所述样品中与IL-3结合的抗体的量,其中抗IL-3-抗体是克隆13。本发明的另外的主题是新型抗体克隆13 ,其为编码所述抗体的核酸和产生抗体克隆13的杂交瘤细胞系。诊断测定试剂盒包含用于进行这种测定的所有必需试剂和材料,优选进行ELISA测定,尤其优选含有抗体克隆13和11。

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