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CH2 DOMAIN TEMPLATE MOLECULES DERIVED FROM RATIONAL GRAFTING OF DONOR LOOPS ONTO CH2 SCAFFOLDS
CH2 DOMAIN TEMPLATE MOLECULES DERIVED FROM RATIONAL GRAFTING OF DONOR LOOPS ONTO CH2 SCAFFOLDS
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机译:CH2域模板分子,其基于捐赠者环在CH2脚手架上的合理嫁接
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摘要
Novel CH2 domain template molecules wherein donor loops from a database of domains are transferred to a CH2 domain scaffold. At least one or up to three loops from a donor are transferred to the CH2 domain. The donor loops may be chosen based on length, e.g., the donor loop may have a length that is similar to that of a structural loop in the CH2 domain scaffold.
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