A kind of waveform physiology signal acquisition device and physiological signal collection mattress. The device can include: waveform flexible body (11) stretches force snesor (12) and signal processing unit (13); The waveform flexible body (11) includes flexible body panel (111) and convex flexible body (112), the convex flexible body (112) is set on flexible body panel (111), and the human pressure born is converted to drawing force; The stretching force snesor (12) is set in flexible body panel (111), generates electric signal according to the drawing force; The signal processing unit (13) carries out the physiological signal that processing obtains human body to the electric signal. Human pressure is converted to electric signal by waveform flexible body (11) and handled by the present invention, thus by it is indirect contacted with human skin in a manner of obtain the physiological signal of human body in daily life, keep the acquisition of physiological signal more convenient.
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