METHOD FOR PREDICTING THE RESPONSE TO TREATMENT WITH RADIOTHERAPY COMBINED WITH CHEMOTHERAPY BASED ON CISPLATIN

摘要

The invention relates to a method for predicting the response to treatment with radiotherapy combined with chemotherapy based on cisplatin in patients suffering from cancer, preferably non-small cell lung cancer, where said method is based on the detection of the presence of methylation of the gene IGFBP-3. The invention also relates to an in vitro method for designing a personalised treatment for an individual suffering from said disease. The method of the invention can be quantitative or semi-quantitative. The invention also relates to a probe for the quantitative detection of the methylation of the gene IGFBP-3, to a kit comprising same, and to the use of said kit for predicting the response of an individual receiving the described treatment..