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BIOCOMPATIBLE AGENT FOR DISPERSING NANOPARTICLES INTO AN AQUEOUS MEDIUM USING MUSSEL ADHESIVE PROTEIN-MIMETIC POLYMER
BIOCOMPATIBLE AGENT FOR DISPERSING NANOPARTICLES INTO AN AQUEOUS MEDIUM USING MUSSEL ADHESIVE PROTEIN-MIMETIC POLYMER
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机译:使用Mussel胶粘剂-类比聚合物将纳米颗粒分散到水性介质中的生物相容性试剂
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摘要
Provided are a mussel adhesive protein-mimetic dispersion stabilizing agent to disperse nanoparticles in an aqueous medium, a colloidal solution including nanoparticles dispersed and stabilized by the dispersion stabilizing agent, and a contrast agent including the colloidal solution. More particularly, the mussel adhesive protein-mimetic dispersion stabilizer is a polyethyleneimine-graft-(poly-ethyleneglycol;polyDOPA) PEI-graft-(PEG;PDOPA). The graft polymer is formed of two parts. One is polyethyleneglycol grafted with a polyethyleneime which has an affinity to an aqueous medium, and the other is polyDOPA which has an affinity to the surface of nanoparticles. Because of those characteristics, the stabilizer shows a stable dispersion of nano particles in the aqueous medium.
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