首页> 外国专利> MEANS AND METHODS FOR DIAGNOSING HEART FAILURE ON THE BASIS OF CHOLESTEROL PARAMETERS, SPHINGOMYELINS AND/OR TRIACYLGLYCEROLS

MEANS AND METHODS FOR DIAGNOSING HEART FAILURE ON THE BASIS OF CHOLESTEROL PARAMETERS, SPHINGOMYELINS AND/OR TRIACYLGLYCEROLS

机译:基于胆固醇参数,鞘磷脂和/或甘油三酯诊断心力衰竭的手段和方法

摘要

The present invention relates to diagnostic means and methods for heart failure. In particular, the invention relates to a method for diagnosing heart failure in a subject suspected to suffer therefrom comprising determining the amount of at least one cholesterol parameter and/or total sphingomyelins and/or triacylglycerols in a sample of the said subject, and comparing the amount(s) determined in step (a) to a reference, whereby it is diagnosed whether the subject suffers from heart failure, or not. Moreover, the invention pertains to a device for diagnosing whether a subject suffers from heart failure, or not, and to the use, in general, of enzymatic detection agents for at least one cholesterol parameter and/or total sphingomyelins and/or triacylglycerols for diagnosing in a sample of a subject whether the said subject suffers from heart failure, or not. Finally, contemplated is a kit for diagnosing heart failure in subject suspected to suffer therefrom.
机译:本发明涉及心力衰竭的诊断手段和方法。特别地,本发明涉及一种在怀疑患有该疾病的受试者中诊断心力衰竭的方法,该方法包括确定所述受试者的样品中至少一种胆固醇参数和/或总鞘磷脂和/或三酰基甘油的量,并比较在步骤(a)中确定的参考量,从而诊断对象是否患有心力衰竭。此外,本发明涉及一种用于诊断受试者是否患有心力衰竭的设备,并且通常涉及用于至少一种胆固醇参数的酶检测剂和/或总鞘磷脂和/或三酰基甘油用于诊断的用途。在受试者的样本中,所述受试者是否患有心力衰竭。最后,考虑了一种用于诊断疑似患有心力衰竭的受试者的试剂盒。

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