首页>
外国专利>
METHODS AND APPARATUS FOR A SHEAR-ENHANCED CNT-ASSEMBLY NANOSENSOR PLATFORM FOR ULTRA-SENSITIVE AND SELECTIVE PROTEIN DETECTION
METHODS AND APPARATUS FOR A SHEAR-ENHANCED CNT-ASSEMBLY NANOSENSOR PLATFORM FOR ULTRA-SENSITIVE AND SELECTIVE PROTEIN DETECTION
展开▼
机译:用于超敏感和选择性蛋白质检测的抗剪切力增强的碳纳米管纳米平台的方法和装置
展开▼
页面导航
摘要
著录项
相似文献
摘要
A nanoscale protein-sensing platform with a non-equilibrium on-off switch that employs dielectrophoretic and hydrodynamic shear forces to overcome these thermodynamic limitations with irreversible kinetics. The detection sensitivity is achieved with complete association of the antibody-antigen-antibody (Ab-Ag-Ab) complex by precisely and rapidly assembling carbon nanotubes (CNT) across two parallel electrodes via sequential DC electrophoresis and dielectrophoresis (DEP), and with single-CNT electron tunneling conductance. The high selectivity is achieved with a critical hydrodynamic shear rate between the activated dissociation shear rates of target and non-target linkers of the aligned CNTs.
展开▼