NEW ACTINOMYCETE INTEGRATIVE AND CONJUGATIVE ELEMENT FROM ACTINOPLANES SP. SE50/110 AS PLASMID FOR GENETIC TRANSFORMATION OF RELATED ACTINOBACTERIA

摘要

The present invention relates to intrinsic DNA sequences in complete genome sequence actinoplanes sp.Which of SE50/110 is similar to the integration of structure actinomyces and conjugative element (AICE). Related AICEs is for establishing genetic manipulation tool for other bacteriums in the past. It in this document, is in specific AICE actinoplanes sp. we describe specific characteristicSE50/110 carry out clearly with any other known AICE as a whole, but share Liao little parties and different sequence similarities and other characterization AiCEs from other species.