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PHENOTYPIC CHARACTERIZATION AND IN SITU GENOTYPING OF A LIBRARY OF GENETICALLY DIFFERENT CELLS
PHENOTYPIC CHARACTERIZATION AND IN SITU GENOTYPING OF A LIBRARY OF GENETICALLY DIFFERENT CELLS
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机译:基因差异细胞文库的表型鉴定和原位基因分型
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摘要
A library of cell strains is characterized by culturing cells at spatially defined and separated positions in a culturing device (1) and determining a phenotypic characteristic of each cell strain in the culturing device (1). The cells are fixated at the spatially defined and separated positions in the culturing device (1) followed by in situgenotyping a respective variable region (150) of each cell strain at the spatially defined and separated positions in the culturing device (1). Each respective phenotypic characteristic is connected to each respective genotype based on the spatially defined and separated positions in the culturing device (1).
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