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IN-KIT PREPARATION OF GALLIUM-68 LABELLED RADIOPHARMACEUTICALS

机译:镓68标记放射性药物的试剂盒制备

摘要

The invention relates to a process for the preparation of complexes of the 68Ga radioisotope in which the complexation reaction between a chelator- functionalised molecule and 68Ga occurs in the presence of a neutralising agent (preferably formate or ascorbate), ascorbic acid and/or salts thereof, a salt of Ga3+ and/or curcumin or a derivative thereof. The invention also relates to a kit for the preparation of a 68Ga complex comprising the necessary reagents for performing the complexation reaction into separate single-dose containers, and instructions for the operator who will perform the complexation reaction.
机译:本发明涉及制备68Ga放射性同位素的配合物的方法,其中在中和剂(优选甲酸或抗坏血酸盐),抗坏血酸和/或其盐的存在下,螯合剂官能化分子与68Ga之间的络合反应发生。 ,Ga 3+和/或姜黄素的盐或其衍生物。本发明还涉及一种用于制备68Ga复合物的试剂盒,该试剂盒包含用于在单独的单剂量容器中进行复合反应的必需试剂,以及用于进行复合反应的操作者的说明。

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