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COMPOSITION FOR CANCER CELL SENSITIZATION CONTAINING AS ACTIVE INGREDIENT SUBSTANCE INHIBITING EXPRESSION OF ONCOGENE OF HPV VIRUS
COMPOSITION FOR CANCER CELL SENSITIZATION CONTAINING AS ACTIVE INGREDIENT SUBSTANCE INHIBITING EXPRESSION OF ONCOGENE OF HPV VIRUS
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机译:包含有效成分以抑制HPV病毒致癌物表达的癌细胞敏感性组合物
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摘要
The present invention relates to a composition for cancer cell sensitization containing as an active ingredient a substance inhibiting the expression of an oncogene of a HPV virus, and more specifically, to a composition for radiosensitization which is used for the treatment of cancer induced by HPV infection and contains as an active ingredient oligonucleotide having any one nucleic acid sequence selected from the group consisting of sequence numbers 1 to 10. The oligonucleotide of the present invention inhibits the expressions of E6 and E7 which are HPV virus oncoproteins, thereby inhibiting the proliferation of tumor cells, and enhances the sensitivity of tumor cells to radiation, thereby exhibiting an excellent effect as a sensitizer that can maximize the cell death effect.
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