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CORTEXOLONE 17ALPHA-VALERATE FOR USE IN THE TREATMENT OF TUMOURS
CORTEXOLONE 17ALPHA-VALERATE FOR USE IN THE TREATMENT OF TUMOURS
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机译:CORTEXOLONE17α-缬草酸酯,用于治疗肿瘤
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摘要
The present invention provides cortexolone 17.alpha.-valerate for use in therapy, in particular for use as an antitumor active ingredient for the curative or adjuvant, or neoadjuvant or palliative treatment of precancerous lesions, dysplasias, metaplasias and tumor diseases, including malignant neoplasias and metastasis as well as for use as an glucocorticoid modulator (in particular an antagonist).;Another aspect of the invention relates to pharmaceutical compositions comprising cortexolone 17.alpha.-valerate as active ingredient and at least one physiologically acceptable excipient for these same therpeutic uses.展开▼
机译:本发明提供了用于治疗的皮质醇酮17.α-戊酸酯,特别是用作抗癌活性成分,用于癌前病变,增生,化生和肿瘤疾病,包括恶性肿瘤的治愈性或辅助性,或新辅助性或姑息性治疗本发明的另一方面涉及药物组合物,其包含皮质酮17.α-戊酸酯作为活性成分和至少一种生理学上可接受的赋形剂,用于这些相同的治疗药物;和/或用作糖皮质激素调节剂(特别是拮抗剂)。用途。 <图像文件=“ IMGA0001.GIF” he =“ 56” imgContent =“ chem” imgFormat =“ GIF” wi =“ 86” /> Chemistry>
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