MULTIFUNCTIONAL COMPOUND SKIN OR WOUND DRESSING AS REGENERATIVE SKIN SUBSTITUTE

摘要

Provided is a new biomimetic skin material with multiple functions and high efficacy. With its unique composite network structure of micro-cavities and microfilaments, the material can mimic the skin barrier function: being capable of shielding contamination, moisture absorption, moisture retention, breathability, pliability and adhesion. The material is capable of not only absorbing wound exudates to facilitate rapid, non-invasive autolytic debridement and bi-directional regulation to ensure sufficient drainage, but also targetedly and compartmentally retaining exudates in the dressing so as to maintain a semi-occlusive local environment with a physiological moisture balance, which is conducive to intercellular and intracellular signal transduction, promoting migration of autologous fibroblasts and epithelial cells, regeneration of granulation tissue and epithelium, accelerating physiological healing and restoration, and reducing recurrence. It has been clinically proven that the dressing material can accelerate the healing of acute skin injuries and chronic ulcer wounds, achieve an excellent healing quality, and avoid or minimize traumatic skin grafting so as to reduce the pain and scarring of patients, as well as to restore the physiological function and appearance of the body.