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HUMANIZED ANTIBODY AGAINST O-ACETYLATED GD2 GANGLIOSIDE (OACGD2)
HUMANIZED ANTIBODY AGAINST O-ACETYLATED GD2 GANGLIOSIDE (OACGD2)
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机译:反对O-乙酰化GD2神经节苷脂的人源化抗体
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摘要
The present invention concerns an antibody, functional fragment, and derivative thereof, which binds specifically to the OAcGD2 ganglioside, said antibody comprising i) a humanized light chain variable region (VL) polypeptide having the amino acid sequence SEQ id n°112; and ii) a humanized heavy chain variable region (VH) having the amino acid sequence SEQ id n°76; and its use in diagnostics and therapy.
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机译:本发明涉及与OAcGD2神经节苷脂特异性结合的抗体,功能片段及其衍生物,所述抗体包含:i)具有氨基酸序列SEQ ID NO:112的人源化轻链可变区(VL)多肽;和ii)具有氨基酸序列SEQ ID n°76的人源化重链可变区(VH);及其在诊断和治疗中的用途。
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