首页> 外国专利> PROCESS FOR PRODUCING POROUS CELLULOSE BEADS USING ALKALI AQUEOUS SOLUTION AND POROUS CELLULOSE BEADS PRODUCED BY THIS PROCESS

PROCESS FOR PRODUCING POROUS CELLULOSE BEADS USING ALKALI AQUEOUS SOLUTION AND POROUS CELLULOSE BEADS PRODUCED BY THIS PROCESS

机译:使用碱水溶液制备多孔纤维素珠的方法以及由该方法制备的多孔纤维素珠

摘要

A process for producing porous cellulose beads of the present invention is characterized by comprising the steps of:a) mixing an alkali aqueous solution and cellulose to prepare cellulose micro dispersion at low temperature,b) adding water to the cellulose micro dispersion to prepare cellulose slurry, andd) bringing the cellulose slurry into contact with coagulation solvent.;A carrier for ligand immobilization of the present invention is characterized by being by shrinking polysaccharide porous beads not less than 10% by a shrinkage rate defined by the following formula, and crosslinking the polysaccharide porous beads: <mrow><mi mathvariant="normal">Shrinkage rate</mi><mspace width="1em" /><mfenced><mo>%</mo></mfenced><mo>=</mo><mfenced separators=""><mn mathvariant="normal">1</mn><mo>−</mo><msub><mi mathvariant="normal">V</mi><mn mathvariant="normal">2</mn></msub><mo>/</mo><msub><mi mathvariant="normal">V</mi><mn mathvariant="normal">1</mn></msub></mfenced><mo>×</mo><mn mathvariant="normal">100</mn></mrow> (wherein, V1 indicates the gel volume of polysaccharide porous beads before shrinkage, and V2 indicates the gel volume of polysaccharide porous beads after shrinkage).
机译:本发明的制备多孔纤维素珠的方法的特征在于包括以下步骤:a)将碱性水溶液和纤维素混合以在低温下制备纤维素微分散体,b)向纤维素微分散体中加水以制备纤维素浆液,和d)使纤维素浆液与凝结溶剂接触。本发明的用于固定配体的载体的特征在于,将多糖多孔珠以下式定义的收缩率收缩不少于10%,并且使多糖交联。多孔珠: <![CDATA [ 收缩率 = 1 < mi mathvariant =“ normal”> V 2 / V < / mi> 1 × 100 ] ]> <图像文件=“ IMGA0001.GIF” he =“ 7” imgContent =“ math” imgFormat =“ GIF” wi =“ 76” /> (其中,V 1 < / Sub>表示收缩前多糖多孔珠的凝胶体积,V 2 表示收缩后的多糖多孔珠)。

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