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PREDICTING RESPONSE TO IMMUNOMODULATORY DRUGS (IMIDS) IN MULTIPLE MYELOMA PATIENTS

机译:预测多发性骨髓瘤患者对免疫调节药物(IMID)的反应

摘要

The present disclosure relates to methods and kits for classifying an individual afflicted with multiple myeloma based on the likelihood of response to immunomodulatory drugs (IMiDs), such as thalidomide and lenalidomide. The disclosure further relates to methods of treating an individual afflicted with multiple myeloma with an IMiD and with methods for determining a therapy regime based on the likelihood of response to an IMiD as a result of genetic characteristic of the patient.
机译:本公开涉及基于对免疫调节药物(IMiD)例如沙利度胺和来那度胺的反应的可能性对患有多发性骨髓瘤的个体进行分类的方法和试剂盒。本公开进一步涉及用IMiD治疗患有多发性骨髓瘤的个体的方法,以及涉及基于由于患者的遗传特征而对IMiD作出响应的可能性来确定治疗方案的方法。

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