首页> 外国专利> METHOD FOR ESTIMATING GLEASON SCORE OF PROSTATE CANCER, METHOD FOR ESTIMATING PATHOLOGICAL STAGE, AND METHOD FOR ACQUIRING SUPPLEMENTARY INFORMATION, ALL ON THE BASIS OF SPECIFIC PSA CONTENT IN SPECIMEN

METHOD FOR ESTIMATING GLEASON SCORE OF PROSTATE CANCER, METHOD FOR ESTIMATING PATHOLOGICAL STAGE, AND METHOD FOR ACQUIRING SUPPLEMENTARY INFORMATION, ALL ON THE BASIS OF SPECIFIC PSA CONTENT IN SPECIMEN

机译:基于标本中特定PSA含量的前列腺癌GLEASON评分估算方法,病理分期估算方法和补充信息获取方法

摘要

The present invention provides methods that are for acquiring various types of supplementary information used for diagnosis or treatment of prostate cancer, and that can be implemented in a less-invasive manner at a low cost. Provided are, by measuring the content of prostate specific antigen (PSA) having a β-N-acetylgalactosamine residue at a non-reducing terminal of a sugar chain in a specimen, and comparing the measured value with a threshold value, (1) a method for estimating whether a Gleason score (primary pattern and secondary pattern) is not less than or less than a prescribed value, (2) a method for estimating whether the pathological stage (pT) is not less than or less than a prescribed value, and (3) a method for acquiring information for assessment indicating diagnosis or treatment should be actively conducted because a GS at gross total removal is expected to be higher than a GS at biopsy.
机译:本发明提供了用于获取用于诊断或治疗前列腺癌的各种类型的补充信息的方法,并且该方法可以以较低侵入性的方式以低成本实现。通过测量样品中糖链非还原端具有β-N-乙酰半乳糖胺残基的前列腺特异性抗原(PSA)的含量,并将其与阈值进行比较,(1)a估计格里森分数(主要模式和次要模式)是否不小于或等于规定值的方法,(2)估计病理阶段(pT)是否不小于或等于规定值的方法, (3)应积极进行获取评估信息以表明诊断或治疗的方法,因为预计总清除量的GS会高于活检的GS。

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