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IN VITRO FULL-SKIN MODEL CONTAINING THREE-DIMENSIONAL CELL CULTURE MODELS OF THE SWEAT GLAND
IN VITRO FULL-SKIN MODEL CONTAINING THREE-DIMENSIONAL CELL CULTURE MODELS OF THE SWEAT GLAND
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机译:包含维腺的三维细胞培养模型的体外全皮肤模型
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摘要
The present disclosure concerns an in-vitro full skin model which comprises a dermal equivalent and epidermal equivalent as well as from about 1 to about 100 three-dimensional sweat gland equivalents with respectively from about 500 to about 500000 sweat gland cells as well as a diameter of respectively from about 100 to about 6000 μm on a supporting layer. Furthermore, the present disclosure concerns the production of the full skin model as well as the use of this model as an in-vitro model, in screening methods as well as for in-vitro evaluation of the influence of cosmetic substances on the inhibition of sweat secretion as well as body odor.
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