NOVEL HETEROCYCLIC COMPOUNDS AS TYROSINE KINASE BCR-ABL INHIBITORS

摘要

The compound or its pharmaceutically acceptable salt of general formula (I) are disclosed, wherein each variable is as described herein. Prepare compound, its pharmaceutical composition are also disclosed, as the method for active constituent, is treating various diseases using the composition, and using compound in the enzymatic activity for manufacturing Drug inhibition ABL1, ABL2 and related chimeric protein.