APPLICATION OF POROUS MATERIALS FOR BACTERIAL QUORUM SENSING INHIBITION/DISRUPTION

摘要

This application relates to the modulation of the flora of bacteria in an environment by inhibiting the quorum sensing of a specific bacteria in said environment by administering an effective amount of a quorum sensing control composition comprising at least one quorum sensing control agent, which is an adsorbent/catalytic inhibitor for a QS signal molecule, such as, N-acyl homoserine lactones (AHL), pseudomonas quinolone signal (PQS), and autoinducer-1 (AI-1), autoinducer-2 (AI-2) type of quorum sensing molecules. Quorum sensing control agents include a sorbent material, sorbent mineral or non-porous mineral such as, for example, phyllosilicate clays, silica, calcite, zeolites, diatomaceous earth, smectite, activated carbon, a nanoparticle or a combination of any of the foregoing. Methods include inhibiting the spoilage of food stuffs and preventing vibriosis in fish or shell fish.