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COLLAGEN-CHONDROITIN SULFATE GEL MATERIAL

机译:胶原-软骨素硫酸盐凝胶材料

摘要

PROBLEM TO BE SOLVED: To develop gel materials in which the form of collagen is fibrillated collagen and, in particular, which have physical properties that make it difficult to contract when used as a cell culture substrate.;SOLUTION: Provided is a collagen-chondroitin sulfate gel material, the gel material comprising collagen and chondroitin sulfate as constituents, the mass ratio thereof being in the range of collagen:chondroitin sulfate=5:1 to 1:3, the form of the component being a complex of cross-linked fibrillated collagen and chondroitin sulfate. But, the cross-linking treatment is at least one cross-linking treatment of γ-ray irradiation, electron beam irradiation, UV irradiation, and plasma irradiation, in the presence of an aqueous solvent, and the complex exhibits a homogeneous appearance.;SELECTED DRAWING: Figure 3;COPYRIGHT: (C)2019,JPO&INPIT
机译:解决的问题:开发一种凝胶材料,其中胶原蛋白的形式为原纤化胶原蛋白,尤其是其物理特性使其在用作细胞培养底物时难以收缩。;解决方案:提供了一种胶原软骨素硫酸盐凝胶材料,该凝胶材料包括胶原蛋白和硫酸软骨素作为成分,其质量比在胶原蛋白:硫酸软骨素= 5:1至1:3的范围内,组分的形式是交联的原纤化的复合物胶原和硫酸软骨素。但是,交联处理是在水性溶剂存在下的γ射线照射,电子束照射,UV照射和等离子体照射中的至少一种交联处理,并且该配合物表现出均质的外观。图纸:图3;版权:(C)2019,JPO&INPIT

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