T cells expressing the gamma delta T cell receptor (TCR) and the chimeric antigen receptor (CAR)

摘要

The present invention provides T cells expressing a gamma delta T cell receptor (TCR) and a chimeric antigen receptor (CAR), wherein CAR is an antigen binding domain; a transmembrane domain; and a costimulatory intracellular signal Wherein the intracellular signaling domain provides a co-stimulatory signal to the T cell following binding to the antigen binding domain of the antigen.Selection drawing None