PROTEIN ENRICHED MICROVESICLES AND METHODS OF MAKING AND USING PROTEIN ENRICHED MICROVESICLES

摘要

To provide protein enriched microvesicles and methods of making and using the same.SOLUTION: The methods include maintaining a cell having a membrane-associated protein comprising a first dimerization domain and a target protein having a second dimerization domain under conditions sufficient to produce a microvesicle from the cell, where the microvesicle includes the target protein. Also provided are cells, reagents and kits that find use in making the microvesicles, as well as methods of using the microvesicles, e.g., in research and therapeutic applications.SELECTED DRAWING: Figure 1