首页> 外国专利> Urothelial cancer and other urogenital organs using N- (4- (6,7-dimethoxyquinolin-4-yloxy) phenyl) -N ′-(4-fluorophenyl) cyclopropane-1,1-dicarboxamide Treatment for malignant tumor

Urothelial cancer and other urogenital organs using N- (4- (6,7-dimethoxyquinolin-4-yloxy) phenyl) -N ′-(4-fluorophenyl) cyclopropane-1,1-dicarboxamide Treatment for malignant tumor

机译:N-(4-(6,7-二甲氧基喹啉-4-基氧基)苯基)-N′-(4-氟苯基)环丙烷-1,1-二甲酰胺治疗尿路上皮癌和其他泌尿生殖器官恶性肿瘤的治疗

摘要

The present disclosure relates to a method for treating urothelial cancer using cabozantinib which is a kinase inhibitor. The present disclosure used a kinase inhibitor N- (4- (6,7-dimethoxyquinolin-4-yloxy) phenyl) -N ′-(4-fluorophenyl) cyclopropane-1,1-dicarboxamide. The present invention relates to a method for treating cancers including urothelial cancer in human patients and other genitourinary malignant tumors. In one aspect, the present invention relates to a method for treating urothelial cancer in a human patient, the method comprising administering to the human patient a therapeutically effective amount of cabozantinib or a pharmaceutically acceptable salt thereof, alone or in combination. Including administration in combination with multiple therapeutic agents. [Selection figure] None
机译:本公开涉及使用作为激酶抑制剂的卡博替尼治疗尿路上皮癌的方法。本公开使用激酶抑制剂N-(4-(6,7-二甲氧基喹啉-4-基氧基)苯基)-N'-(4-氟苯基)环丙烷-1,1-二甲酰胺。本发明涉及一种在人类患者中治疗包括尿路上皮癌和其他泌尿生殖系统恶性肿瘤的癌症的方法。在一个方面,本发明涉及一种用于治疗人类患者尿路上皮癌的方法,该方法包括向人类患者单独或组合给予治疗有效量的卡博替尼或其药学上可接受的盐。包括与多种治疗剂联合给药。 [选择图]无

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