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TREATING ORAL LESIONS USING PLACENTAL EXTRACELLULAR MATRIX

机译:使用胎盘中央细胞外基质治疗口腔病变

摘要

To provide novel collagen-containing compositions for treatment of oral lesions.SOLUTION: A method for treating an individual having an oral lesion comprises administering to the oral lesion a therapeutically effective amount of extracellular matrix. The extracellular matrix is human placental extracellular matrix that has not been chemically modified or contacted with an exogenous protease. The extracellular matrix preferably has been prepared by treatment with a surfactant. The extracellular matrix preferably comprises collagen, and further preferably comprises one or more selected from among laminin, fibronectin, elastin and glycosaminoglycan.SELECTED DRAWING: Figure 1
机译:为了提供用于治疗口腔损伤的新型的含胶原的组合物。解决方案:一种用于治疗具有口腔损伤的个体的方法,该方法包括向口腔损伤给予治疗有效量的细胞外基质。细胞外基质是未经化学修饰或未与外源蛋白酶接触的人胎盘细胞外基质。细胞外基质优选已经通过用表面活性剂处理而制备。细胞外基质优选包含胶原蛋白,并且还优选包含选自层粘连蛋白,纤连蛋白,弹性蛋白和糖胺聚糖中的一种或多种。

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