首页> 外国专利> DRUG FOR TREATMENT OF INFANT HYPERBILIRUBINEMIA OR SYMPTOMS THEREOF CONTAINING STANNSOPORFIN

DRUG FOR TREATMENT OF INFANT HYPERBILIRUBINEMIA OR SYMPTOMS THEREOF CONTAINING STANNSOPORFIN

机译:药物用于治疗婴儿高胆双血症或含斯坦诺泊汀的症状

摘要

To provide drugs for the treatment of infant hyperbilirubinemia or the symptoms thereof.SOLUTION: The present invention comprises administering a therapeutic amount of stannsoporfin to an infant with hyperbilirubinemia where at least one of a baseline total bilirubin level is elevated above a predetermined threshold and at least one risk factor is present, the at least one risk factor being a hemolytic disease, the predetermined threshold being 1-3 mg/dL below a threshold for administration of phototherapy according to the 2004AAP nomogram corresponding to an infant age, and the therapeutic amount of stannsoporfin being 0.75 mg/kg to 5 mg/kg based on an infant body weight.SELECTED DRAWING: None
机译:提供用于治疗婴儿高胆红素血症或其症状的药物。解决方案:本发明包括向患有高胆红素血症的婴儿施用治疗量的锡泊芬,其中基线总胆红素水平中的至少一个升高到预定阈值以上并且至少存在一种危险因素,所述至少一种危险因素是溶血性疾病,预定阈值比根据对应于婴儿年龄的2004AAP nomogram的光疗阈值低1-3 mg / dL,并且锡泊芬为0.75毫克/千克至5毫克/千克,基于婴儿体重。

著录项

  • 公开/公告号JP2019052176A

    专利类型

  • 公开/公告日2019-04-04

    原文格式PDF

  • 申请/专利权人 INFACARE PHARMACEUTICAL CORP;

    申请/专利号JP20180227108

  • 发明设计人 SIMON J TULLOCH;WARREN W WASIEWSKI;

    申请日2018-12-04

  • 分类号A61K31/555;A61K41;A61P1/16;A61P7;A61P43;

  • 国家 JP

  • 入库时间 2022-08-21 12:22:49

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