Dietary-controlled expression of nucleic acids encoding apoptosis promoting proteins

摘要

The present invention relates to a regulatory polynucleotide comprising a minimal promoter and at least one AARE (amino acid response element) nucleic acid for the controlled expression of a nucleic acid encoding a pro-apoptotic protein in an individual, wherein: The regulatory polynucleotide comprises a nucleic acid encoding a pro-apoptotic protein which is activated in the individual in response to the intake of a meal lacking at least one essential amino acid, and which is placed under the control of said regulatory polynucleotide. , The above-mentioned nucleic acid. 【Selection chart】 None