Cancer diagnosis and treatment method

摘要

The present invention provides diagnostic and therapeutic methods and compositions for cancer. The present invention is directed to a method of determining whether a patient suffering from cancer is likely to respond to a treatment comprising a MAPK signaling inhibitor, to a treatment comprising one or more MAPK signaling inhibitors. Methods of predicting responsiveness of patients suffering from cancer, methods of selecting a treatment for patients suffering from cancer, and expression levels of the biomarkers of the invention (e.g., DUSP6, ETV4, SPRY2 , SPRY4, PHLDA1, ETV5, DUSP4, CCND1, EPHA2, and EPHA4 expression levels) are provided to provide a method of treating cancer. 【Selection chart】 None